Symbol
Name
ID

Mir155
microRNA 155
MGI:2676840

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Mouse Phenotypes

increased B cell proliferation

thymus hyperplasia

enlarged spleen

increased spleen weight

abnormal lymphopoiesis

abnormal class switch recombination

abnormal T-helper 17 cell differentiation

extramedullary hematopoiesis

decreased germinal center B cell number

increased germinal center B cell number

increased B cell number

increased pre-B cell number

decreased T-helper 17 cell number

increased T-helper 2 cell number

decreased effector memory T-helper cell number

decreased regulatory T cell number

decreased leukocyte cell number

abnormal CD4-positive, alpha beta T cell morphology

abnormal T-helper 1 cell morphology

intermingled spleen red and white pulp

abnormal spleen B cell follicle morphology

decreased spleen germinal center number

decreased spleen germinal center size

decreased spleen white pulp amount

increased spleen white pulp amount

abnormal B cell physiology

abnormal germinal center B cell physiology

decreased IgG1 level

decreased IgM level

abnormal T cell physiology

abnormal CD4-positive, alpha-beta T cell physiology

Availability

Mouse Genotype

Gt(ROSA)26Sor^{tm1(Mirn155)Rsky}/Gt(ROSA)26Sor^{tm1(Mirn155)Rsky}

Mir155^tm1.1Brd/Mir155^tm1.1Brd

Mir155^tm1.1Rsky/Mir155^tm1.1Rsky

Mir155^tm1Brd/Mir155^tm1Brd

Mir155^tm1Rsky/Mir155^tm1Rsky

Tg(Igh-Mir155)8Cro/0

Tg(Igh-Mir155)10Cro/0

Gt(ROSA)26Sor^{tm1(tTA,tetO-Mir155)Fjsl}/Gt(ROSA)26Sor⁺
Tg(Nes-cre)1Wmz/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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